Epilepsy is characterized by seizures, it is important for people suffering from Epilepsy to understand seizures as it can significantly help the person understand the therapy. Seizures can be categorized as generalized seizures and focal seizures. There are many symptoms related to seizures and to help understand them better, they have been categorized into various sectors one of them is motor capability. What may happen during a seizure mostly depends on the part of the brain it affects, it is this factor which defines what symptoms may be observed and how the individual may get affected, and it also helps us determine the right kind of medication. The other important criterion is to know whether or not the affected person was conscious during the whole thing. Whether the person moves or not during the seizure helps us define the Motor Symptoms, and Non-motor symptoms. Generally these classifications do not have any use while discussing seizures though in many cases and while understanding the exact type, these seizures come in handy.

The motor symptoms in the seizures are usually defined by the rhythmical jerking which is either  prolonged (clonic), characterized by limping as muscles become weak (atonic), tension and rigidity in the muscles (tonic), twitching (myoclonus), or are characterized by constant contraction and relaxation which is also known as epileptic spasm. The non-motor symptoms known as absence seizures can be either Typical or Atypical. In absence seizure sometimes, the affected person can experience a transient twitching which is usually contained in a specific part of the body for example Eyelids. Another reason why people need to understand the scientific side of Epilepsy is that there is a lot of stigmas still prevailing on its part in various countries.  as

Now, let’s come to the most important aspect of Epilepsy, the treatment part of it. Amongst the wide variety of treatment management options available, a drug quite in use is Ativan (Lorazepam) 2mg tablets.

Ativan is a widely used option for effective management of Epilepsy. The far and wide use of this medication in epilepsy is due to its potent ability to bring down the intensity of seizures and make the person feel calm. This drug may not be useful in decreasing the frequency of seizures though it does mitigate the seizure in short period and thus prevents any large damage done by the seizure.

Lorazepam belongs to the therapeutic category of benzodiazepine medications. This drug binds to its BDZ receptor which is located on the GABA ion complex; the new receptor ion complex thus formed has an increased affinity towards the neurotransmitter called GABA which has inhibitory functions. It opens up the chloride channels and leads to their influx which causes the hyperpolarization of the membrane. The hyperpolarized membrane cuts down the unnecessary excitatory response and brings about muscle relaxation, and calming effects in the brain and body.

Ativan is available in 0.5mg, 1mg and 2 mg of dosing strengths as a tablet formulation which is meant to be taken orally with water. The usual starting dose is 1.5 mg each day taken as three 0.5mg divided doses. In adults, the therapy can be maintained with 8mg to 10mg taken in divided. Do not take this dose to be the substitute of doctor’s prescription.

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Some adverse effects of this medication are sleepiness, dizziness, confusion, violent behavior, weakness, slurred speech, delusion, and unusual behavior.

Preventive steps to be taken:

1.  Do not take this medication if you are pregnant or planning to get pregnant as this drug may harm the baby.

2.  Refrain from taking this medication if you are breast-feeding a child as this medication can pass through the breast milk and harm the feeding baby.  

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