Arthritis is a condition that affects joints and is characterized by inflammation. Literally, it means inflammation of one or more than one joint; it is often followed by pain. Since joints are related to movement, Arthritis also leads to restriction of mobility in many. It is a vast condition and is said to have about 100 types. On the basis of how many joints are affected, this condition can be classified as monoarthritis (single joint), oligoarthritis (two or three joints) and polyarthritis (more four or more).

The other classifications are based on various factors such as wear and tear of cartilages the best example of which is osteoarthritis and then there is inflammation resulting from autoimmune disorders the best example of which is rheumatoid arthritis. All these types of Arthritis as a whole constitute to be the most prevalent chronic condition in the USA.

What causes arthritis mostly depends on the type or form of arthritis. There are various causes which lead to various types of arthritis such as mostly injury leads to osteoarthritis, some metabolic disorders can lead to gout and pseudogout, autoimmune disorders can lead to rheumatoid arthritis, etc. All the types of arthritis can be termed to be individual kind of illnesses having varying features, treatments, prognoses and complications. What they have in common is their tendency to affect the joints, ligaments, muscles, cartilage, and tendons. The most common symptoms are pain and restriction of mobility of joints, the inflammation is characterized by swelling, stiffness, redness, warmth, and pain. In many forms of arthritis, the common treatment option involves treatment of inflammation and pain, the most potent option for this condition is Medrol (Methylprednisolone) 4mg tablets.

Medrol is a powerful therapy used for the effective management of various inflammatory conditions such as Arthritis, Osteoarthritis, Gout, Multiple Sclerosis, Asthma, COPD and numerous dermatological conditions. This drug has potent inflammatory properties and acts by reducing the pain, swelling, redness, and heat arising from the affected areas such as joints. Medrol is a faster and longer acting medication which is the reason for its massive use. It contains Methylprednisolone as its key remedial agent which is also included in the WHO list of essential medication.

Methylprednisolone is corticosteroid category medication which exerts its response by binding with the specific cytoplasm receptors with high affinity, this binding result in the alteration of the transcription and protein synthesis process which inhibits the infiltration of leukocyte and other inflammatory factors thus reducing inflammation. Another pathway through which this drug acts is by the inhibition of Phospholipase-A2, lipocortins, etc. which have a leading role to play in the flaring the inflammation.  

Medrol is a tablet preparation which should be ingested with water; it is available in a number of doing strengths such as 4, 16 and 32mg. For the management of Rheumatoid Arthritis, the most use dose is 4 to 48 mg orally taken once a day or in divided doses. Usual therapy for Gout is 4 to 48 mg orally once a day. TO manage the exacerbation of Multiple Sclerosis, the most preferred therapy is 200 mg for a week which is then reduced to 80 mg every other day for 1 month. Dose presented here is only initial dose and is not to be taken as alternative towards doctor's prescription.

Some adverse effects of this medication are tarry stools, weight gain, cramps, constipation and increased urination. 

See Also:- Effectively Control Arthritis or Other Inflammatory Condition Using Medrol

Preventive measures:

1. This is a steroid medication which when used for long can weaken the immune system; this can get you prone to infections. Talk to your doctor to know more. 

2. This drug can increase the blood glucose levels; you are advised to keep notice of your sugar levels especially if you are suffering from Diabetes.

3. It is not clearly known whether Medrol can affect an unborn baby or pass through breast milk; tell your doctor if you are pregnant or breastfeeding a baby.  

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